Altered local coherence in the default mode network due to sevoflurane anesthesia

The Default Mode Network and Altered Consciousness in Epilepsy

The default mode network has been hypothesized based on the observation that specific regions of the brain are consistently activated during the resting state and deactivated during engagement with task. The primary nodes of this network, which typically include the precuneus/posterior cingulate, the medial frontal and lateral parietal cortices, are thought to be involved in introspective and s...

Brain's Default Mode Network

Altered Resting-State Default Mode Network Connectivity in Adults Prenatally Exposed to Alcohol

Introduction The recently characterized default mode network (DMN), described as consistent regions of higher activation during rest than during cognition [1], has been found to be altered in the resting state in several clinical populations [2,3]. Additionally, DMN deactivation during cognitive demand has been shown to be impaired in a subset of clinical conditions due to an inability to redis...

The Default Mode Network in Autism.

Autism spectrum disorder (ASD) is characterized by deficits in social communication and interaction. Since its discovery as a major functional brain system, the default mode network (DMN) has been implicated in a number of psychiatric disorders, including ASD. Here we review converging multimodal evidence for DMN dysfunction in the context of specific components of social cognitive dysfunction ...

Altered default mode network connectivity in Alzheimer's disease--a resting functional MRI and Bayesian network study.

A number of functional magnetic resonance imaging (fMRI) studies reported the existence of default mode network (DMN) and its disruption due to the presence of a disease such as Alzheimer's disease (AD). In this investigation, first, we used the independent component analysis (ICA) technique to confirm the DMN difference between patients with AD and normal control (NC) reported in previous stud...